Site-specific PEGylation of native disulfide bonds in therapeutic proteins

References

Page 1

	Year	Citations
Rational Design of a Potent, Long-Lasting Form of Interferon: A 40 kDa Branched Polyethylene Glycol-Conjugated Interferon α-2a for the Treatment of Hepatitis C Pascal Bailon, Alicia V. Palleroni, Carol Ann Schaffer, Bioconjugate Chemistry Interferon Alpha-2aTranslational MedicineEthylene GlycolHepatologyHepatitis C	2001	609
Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding. Don Healey, L Dianda, John P. Moore, The Journal of Experimental Medicine Viral ReplicationCd4+ CellsImmunologyCell FusionVirus Binding	1990	212
Structural and Biologic Characterization of Pegylated Recombinant IFN- <i>α</i> 2b Michael J. Grace, Stephen K. Youngster, Gerry Gitlin, Journal of Interferon & Cytokine Research	2001	174
Site of Pegylation and Polyethylene Glycol Molecule Size Attenuate Interferon-α Antiviral and Antiproliferative Activities through the JAK/STAT Signaling Pathway Michael J. Grace, Seoju Lee, Sheri Bradshaw, Journal of Biological Chemistry	2005	87
Site-directed chemical modification and crosslinking of a monoclonal antibody using equilibrium transfer alkylating crosslink reagents Frederick A. Liberatore, Robert D. Comeau, James M. McKearin, Bioconjugate Chemistry Preclinical TherapeuticsImmunologyAltmetric Attention ScorePeptide ScienceImmunotherapeutics	1990	54
Molecular yardsticks. Synthesis of extended equilibrium transfer alkylating cross-link reagents and their use in the formation of macrocycles Stephen Brocchini, Martin Eberle, Richard Lawton Journal of the American Chemical Society Combinatorial ChemistryCross-coupling ReactionMolecular SciencesEngineeringMolecular Yardsticks	1988	52
Development of sensitive radioiodinated anti-sense oligonucleotide probes by conjugation techniques Mrinal K. Dewanjee, A. K. Ghafouripour, Rudolf Werner, Bioconjugate Chemistry	1991	28
Replacement of the interchain disulfide bridge-forming amino acids A7 and B7 by glutamate impairs the structure and activity of insulin Zhan‐Yun Guo, Xiao‐Yuan Jia, You-Min Feng Biological Chemistry	2004	10

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