Site-specific PEGylation of native disulfide bonds in therapeutic proteins

Rational Design of a Potent, Long-Lasting Form of Interferon:  A 40 kDa Branched Polyethylene Glycol-Conjugated Interferon α-2a for the Treatment of Hepatitis C

Pascal Bailon, Alicia V. Palleroni, Carol Ann Schaffer et al. · Bioconjugate Chemistry · 2001 · 609 citations

Interferon Alpha-2a, Translational Medicine, Ethylene Glycol +15

Novel anti-CD4 monoclonal antibodies separate human immunodeficiency virus infection and fusion of CD4+ cells from virus binding.

Don Healey, L Dianda, John P. Moore et al. · The Journal of Experimental Medicine · 1990 · 212 citations · Full text

Viral Replication, Cd4+ Cells, Immunology +18

Structural and Biologic Characterization of Pegylated Recombinant IFN- <i>α</i> 2b

Michael J. Grace, Stephen K. Youngster, Gerry Gitlin et al. · Journal of Interferon & Cytokine Research · 2001 · 174 citations

Site of Pegylation and Polyethylene Glycol Molecule Size Attenuate Interferon-α Antiviral and Antiproliferative Activities through the JAK/STAT Signaling Pathway

Michael J. Grace, Seoju Lee, Sheri Bradshaw et al. · Journal of Biological Chemistry · 2005 · 87 citations · Full text

Site-directed chemical modification and crosslinking of a monoclonal antibody using equilibrium transfer alkylating crosslink reagents

Frederick A. Liberatore, Robert D. Comeau, James M. McKearin et al. · Bioconjugate Chemistry · 1990 · 54 citations

Preclinical Therapeutics, Immunology, Altmetric Attention Score +22