Site-specific PEGylation of native disulfide bonds in therapeutic proteins

Sunil Shaunak, Antony Godwin, Ji-Won Choi, +7

Nature Chemical Biology

Protein ChemistryProtein AssemblyBiochemistryNatural SciencesBioconjugation +2

Periodic Activation of Wnt/β-Catenin Signaling Enhances Somatic Cell Reprogramming Mediated by Cell Fusion

Elisa Pedone, Stefano Pepe, Maria Pia Cosma

Cell stem cell

Signal TransductionDevelopmental BiologySignaling PathwayCell RegulationCell Interaction +7

The senotherapeutic drug ABT-737 disrupts aberrant p21 expression to restore liver regeneration in adult mice

Birgit Ritschka, Tania Knauer-Meyer, Daniel Sampaio Gonçalves, +8

Genes & Development

Oxidative Modification of Low-Density Lipoprotein and Atherogenetic Risk in β-Thalassemia

Maria A. Livrea, Luisa Tesoriere, Aurelio Maggio, +3

Blood

Regulation of Gene Expression and Signaling Pathway Activity in Mammalian Cells by Automated Microfluidics Feedback Control

Lorena Postiglione, Sara Napolitano, Elisa Pedone, +6

ACS Synthetic Biology

EngineeringSynthetic CircuitOrgan-on-a-chipGene Regulatory NetworkCellular Physiology +21

T-cell factor 3 (Tcf3) deletion increases somatic cell reprogramming by inducing epigenome modifications

Luigi Ombrato, Elisa Pedone, Stefano Pepe, +2

Proceedings of the National Academy of Sciences

A tunable dual-input system for on-demand dynamic gene expression regulation

Elisa Pedone, Lorena Postiglione, Francesco Aulicino, +6

Nature Communications

β-Catenin Fluctuates in Mouse ESCs and Is Essential for Nanog-Mediated Reprogramming of Somatic Cells to Pluripotency

Lucia Marucci, Elisa Pedone, Umberto Di Vicino, +3

Cell Reports

An information rich biomedical polymer library

Elisa Pedone, Xiongwei Li, Neli Koseva, +2

Journal of Materials Chemistry

Macromolecular ChemistryEngineeringPrecursor PolymerOrganic ChemistryChemistry +18

Oxidation resistance of LDL is correlated with vitamin E status in β-thalassemia intermedia

Luisa Tesoriere, Daniele D’Arpa, Aurelio Maggio, +3

Atherosclerosis

BiochemistryOxidation ResistanceMedicineLipid PeroxidationPhysiology +6