The extra- and intracellular barriers to lipid and adenovirus-mediated pulmonary gene transfer in native sheep airway epithelium

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid

Joseph Zabner, A Fasbender, Tom Moninger et al. · Journal of Biological Chemistry · 1995 · 1.4K citations · Full text

Pharmacy, Biotechnology, Molecular Biology +16

A novel cationic liposome reagent for efficient transfection of mammalian cells

Xiang Gao, Leaf Huang · Biochemical and Biophysical Research Communications · 1991 · 845 citations

Pharmacy, Biotechnology, Pharmaceutics +16

Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis

Ronald G. Crystal, Noel G. McElvaney, Melissa A. Rosenfeld et al. · Nature Genetics · 1994 · 830 citations

Medicine, Molecular Biology, Molecular Genetics +12

Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis

Natasha J. Caplen, Eric W.F.W. Alton, Peter G. Mddleton et al. · Nature Medicine · 1995 · 707 citations

Pharmacy, Genetics, Molecular Biology +14

Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis

Joseph Zabner, Larry A. Couture, Richard J. Gregory et al. · Cell · 1993 · 680 citations

Medicine, Genetics, Molecular Biology +14