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Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease

Mónica García‐Alloza, Elissa M. Robbins, Sandy Zhang-Nunes, Susan M. Purcell, Rebecca A. Betensky, Susan Raju, Claudia Prada, Steven M. Greenberg, Brian J. Bacskai, Matthew P. Frosch

Neurobiology of Disease · 2006 · 748 citations · 37 references

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37

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Karen Hsiao, Paul F. Chapman, Steven P. Nilsen et al. · Science · 1996 · 4.2K citations

, , +17

Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

Salvatore Oddo, Antonella Caccamo, Jason D. Shepherd et al. · Neuron · 2003 · 4.1K citations · Full text

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Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

Donalyn Scheuner, Christopher B. Eckman, M. Jensen et al. · Nature Medicine · 1996 · 2.6K citations

, , +16

Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported

Denis A. Evans · JAMA · 1989 · 1.6K citations

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Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson et al. · Human Molecular Genetics · 2003 · 1.6K citations · Full text

, , +16