Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel, +3

Nature

Natural SciencesRna SplicingRna BiologyDna ReplicationMolecular Biology +7

Disruption of epithelial cell-matrix interactions induces apoptosis

SM Frisch, H. Francis

The Journal of Cell Biology

Anchorage IndependenceCell RegulationTumor MicroenvironmentCell InteractionCell-matrix Interactions +13

Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms

Azad Bonni, Anne Brunet, Anne E. West, +3

Science

The extracellular matrix as a cell survival factor.

Jere E. Meredith, Bahare Fazeli, Martin A. Schwartz

Molecular Biology of the Cell

Undergo PcdCell SignalingCell AdhesionApoptosisImmunology +13

Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity

Philippe Bouillet, Donald Metcalf, David C.S. Huang, +5

Science

Clinical ImmunologyCertain Apoptotic ResponsesPreclude AutoimmunityLymphocyte DevelopmentApoptosis +16

Bim: a novel member of the Bcl-2 family that promotes apoptosis

Liam O’Connor

The EMBO Journal

Cell RegulationApoptosisCell DeathBcl-2 FamilyNovel Member +4

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

Asim Khwaja

The EMBO Journal

Signal TransductionPhosphoinositide 3-Oh KinaseSignaling PathwayCell RegulationMedicine +13

The Proapoptotic Activity of the Bcl-2 Family Member Bim Is Regulated by Interaction with the Dynein Motor Complex

Hamsa Puthalakath, David C.S. Huang, LORRAINE A. O'REILLY, +2

Molecular Cell

Signal TransductionProapoptotic ActivityCell DeathCellular BiologyCytoskeleton +7

Bmf: A Proapoptotic BH3-Only Protein Regulated by Interaction with the Myosin V Actin Motor Complex, Activated by Anoikis

Hamsa Puthalakath, Andreas Villunger, Lorraine A. O’Reilly, +5

Science

Molecular RegulationApoptosisMolecular BiologyCell DeathCytoskeleton +18

Activation of the ERK1/2 Signaling Pathway Promotes Phosphorylation and Proteasome-dependent Degradation of the BH3-only Protein, Bim

Rebecca Ley, Kathryn Balmanno, Kathryn Hadfield, +2

Journal of Biological Chemistry