MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Dominique Bonnet, John E. Dick · Nature Medicine · 1997 · 6.9K citations

Hematological Malignancy, Chromatin, Cell Division +10

Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

Brian Druker, Moshe Talpaz, Debra Resta et al. · New England Journal of Medicine · 2001 · 5.2K citations · Full text

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

Tsvee Lapidot, Christian Sirard, Josef Vormoor et al. · Nature · 1994 · 4.7K citations

Cell Therapy, Transplantation, Marrow Transplantation +11

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

Koichi Akashi, David Traver, Toshihiro Miyamoto et al. · Nature · 2000 · 2.5K citations

Hematological Malignancy, Developmental Biology, Cytogenetics +11

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

Allen Eng Juh Yeoh, Mary Elizabeth Ross, Sheila Shurtleff et al. · Cancer Cell · 2002 · 1.9K citations · Full text

Bioinformatics, Hematological Malignancy, Engineering +13