Renee D. Wright

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl

Ellen Weisberg, Paul W. Manley, Werner Breitenstein et al. · Cancer Cell · 2005 · 1.5K citations · Full text

Molecular Pharmacology, Mutant Bcr-abl, Medicine +5

Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix

Loren D. Walensky, Andrew L. Kung, Iris Escher et al. · Science · 2004 · 1.3K citations · Full text

Hydrocarbon-stapled Bh3 Helix, Protein Function, Hydrocarbon Stapling +12

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy

Abdel Kareem Azab, Judith Runnels, Costas Pitsillides et al. · Blood · 2009 · 419 citations · Full text

HOXA9 is required for survival in human MLL-rearranged acute leukemias

Joerg Faber, Andrei V. Krivtsov, Matthew C. Stubbs et al. · Blood · 2008 · 327 citations · Full text

Inhibition of USP10 induces degradation of oncogenic FLT3

Ellen Weisberg, Nathan J. Schauer, Jing Yang et al. · Nature Chemical Biology · 2017 · 149 citations · Full text

Oncogenic Agent, Natural Sciences, Molecular Biology +3