Over-Expression of LSD1 Promotes Proliferation, Migration and Invasion in Non-Small Cell Lung Cancer

Tangfeng Lv, Dongmei Yuan, Xiaohui Miao, Yanling Lv, Ping Zhan, Xiaokun Shen, Yong Song

PLoS ONE · 2012 · 266 citations · 18 references

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Abstract

Over-expression of LSD1 was associated with poor prognosis in NSCLC, and promoted tumor cell proliferation, migration and invasion. These results suggest that LSD1 is a tumor-promoting factor with promising therapeutic potential for NSCLC.

References

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