Concepedia

Warfarin Dosage Response Related Pharmacogenetics in Chinese Population

Siyue Li, Yuangao Zou, Xia Wang, Xunbei Huang, Yong Sun, Yuqing Wang, Li Dong, Hong Jiang

PLoS ONE · 2015 · 38 citations · 27 references

DOIFull text

Open access

Abstract

A better understanding of the genetic variants in individuals can be the foundation of warfarin dosing algorithm and facilitate the reasonable and effective use of warfarin in Chinese.

References

27

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The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen

Elizabeth Sconce, Tayyaba Khan, Hilary Wynne et al. · Blood · 2005 · 945 citations · Full text

A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin

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Michael D. Caldwell, Tarif Awad, Julie A. Johnson et al. · Blood · 2008 · 519 citations · Full text