Concepedia

Immunopositivity for Histone MacroH2A1 Isoforms Marks Steatosis-Associated Hepatocellular Carcinoma

Francesca Rappa, Azzura Greco, Christine Podrini, Francesco Cappello, Michelangelo Foti, Lucie Bourgoin, Marion Peyrou, Arianna Marino, Nunzia Scibetta, Roger Williams,

PLoS ONE · 2013 · 70 citations · 29 references

DOIFull text

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Abstract

These data obtained in mice and humans suggest that both macroH2A1 isoforms may play a role in HCC pathogenesis and moreover may be considered as novel diagnostic markers for human HCC.

References

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Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

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Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production

Willscott E. Naugler, Toshiharu Sakurai, Sunhwa Kim et al. · Science · 2007 · 1.9K citations

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Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

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Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

Yasuo Horie, Akira Suzuki, Ei Kataoka et al. · Journal of Clinical Investigation · 2004 · 659 citations