Toshiharu Sakurai

Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production

Willscott E. Naugler, Toshiharu Sakurai, Sunhwa Kim et al. · Science · 2007 · 1.9K citations

Den Administration, Immunology, Pathology +21

Hepatocyte Necrosis Induced by Oxidative Stress and IL-1α Release Mediate Carcinogen-Induced Compensatory Proliferation and Liver Tumorigenesis

Toshiharu Sakurai, Guobin He, Atsushi Matsuzawa et al. · Cancer Cell · 2008 · 482 citations · Full text

Inflammation, Hepatology, Liver Tumorigenesis +12

Hepatocyte IKKβ/NF-κB Inhibits Tumor Promotion and Progression by Preventing Oxidative Stress-Driven STAT3 Activation

Guobin He, Guann‐Yi Yu, Vladislav Temkin et al. · Cancer Cell · 2010 · 425 citations · Full text

Inflammation, Cancer Research, Reductive Stress +11

Loss of hepatic NF-κB activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation

Toshiharu Sakurai, Shin Maeda, Lufen Chang et al. · Proceedings of the National Academy of Sciences · 2006 · 403 citations · Full text

Lenvatinib as an Initial Treatment in Patients with Intermediate-Stage Hepatocellular Carcinoma Beyond Up-To-Seven Criteria and Child–Pugh A Liver Function: A Proof-Of-Concept Study

Masatoshi Kudo, Kazuomi Ueshima, Stephan Chan et al. · Cancers · 2019 · 291 citations · Full text