Toshiharu Sakurai

Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production

Willscott E. Naugler, Toshiharu Sakurai, Sunhwa Kim et al. · Science · 2007 · 2K citations

Life Sciences, Immunology, Oncology +17

Hepatocyte Necrosis Induced by Oxidative Stress and IL-1α Release Mediate Carcinogen-Induced Compensatory Proliferation and Liver Tumorigenesis

Toshiharu Sakurai, Guobin He, Atsushi Matsuzawa et al. · Cancer Cell · 2008 · 483 citations · Full text

Medicine, Immunology, Oncology +16

Hepatocyte IKKβ/NF-κB Inhibits Tumor Promotion and Progression by Preventing Oxidative Stress-Driven STAT3 Activation

Guobin He, Guann‐Yi Yu, Vladislav Temkin et al. · Cancer Cell · 2010 · 431 citations · Full text

Life Sciences, Cell Biology, Oncology +13

Loss of hepatic NF-κB activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation

Toshiharu Sakurai, Shin Maeda, Lufen Chang et al. · Proceedings of the National Academy of Sciences · 2006 · 405 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Lenvatinib as an Initial Treatment in Patients with Intermediate-Stage Hepatocellular Carcinoma Beyond Up-To-Seven Criteria and Child–Pugh A Liver Function: A Proof-Of-Concept Study

Masatoshi Kudo, Kazuomi Ueshima, Stephan Chan et al. · Cancers · 2019 · 298 citations · Full text

Medicine, Oncology, Surgery +14