Concepedia
Bioorganic & Medicinal Chemistry Letters · 2009 · 22 citations · 18 references
Open access
Drug TargetBiochemistryNatural SciencesMedicineRational Drug DesignMechanism Of ActionChemical BiologyPharmacologyMolecular ModelingPharmaceutical ChemistryInhibitory ActivityDrug Discovery
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Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.8K citations
Cent Inhibition, Inhibitory Activity, Biochemistry +8
Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function
Garrett M. Morris, David S. Goodsell, Robert S. Halliday et al. · Journal of Computational Chemistry · 1998 · 10.7K citations
Engineering, Molecular Biology, Computational Chemistry +22
A Critical Assessment of Docking Programs and Scoring Functions
Gregory L. Warren, C. Webster Andrews, Anna‐Maria Capelli et al. · Journal of Medicinal Chemistry · 2005 · 1.7K citations
Engineering, Molecular Biology, Scoring Functions +23
Requirement for Glycine in Activation of NMDA-Receptors Expressed in <i>Xenopus</i> Oocytes
Nancy W. Kleckner, Raymond Dingledine · Science · 1988 · 1.4K citations
Comparison of Shape-Matching and Docking as Virtual Screening Tools
Paul C. D. Hawkins, A. Geoffrey Skillman, Anthony Nicholls · Journal of Medicinal Chemistry · 2006 · 994 citations
Hit Identification, Molecular Biology, Shape Analysis +24