The Mitochondrial Targeting Chaperone 14-3-3ε Regulates a RIG-I Translocon that Mediates Membrane Association and Innate Antiviral Immunity

A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.3K citations

Inflammation, Mitochondrial Function, Cell Death +7

Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine

Anthony J. Muslin, J. William Tanner, Paul M. Allen et al. · Cell · 1996 · 1.4K citations · Full text

Proteins Is, Signal Transduction, Signaling Pathway +9

Regulating Intracellular Antiviral Defense and Permissiveness to Hepatitis C Virus RNA Replication through a Cellular RNA Helicase, RIG-I

Rhea Sumpter, Yueh–Ming Loo, Eileen Foy et al. · Journal of Virology · 2005 · 886 citations · Full text

Viral Replication, Cellular Rna Helicase, Immunology +18

Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

Michaela U. Gack, Randy A. Albrecht, Tomohiko Urano et al. · Cell Host & Microbe · 2009 · 855 citations · Full text

Virus Structure, Ubiquitin Ligase Trim25, Molecular Biology +5

Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity

Evelyn Dixit, Steeve Boulant, Yijing Zhang et al. · Cell · 2010 · 807 citations · Full text

Antiviral Innate Immunity, Pathogenesis, Immunology +7