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The serial cultivation of human diploid cell strains

Leonard Hayflick, Paul S. Moorhead · Experimental Cell Research · 1961 · 8.4K citations

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

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Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

Mariela Jaskelioff, Florian L. Müller, Ji-Hye Paik et al. · Nature · 2010 · 835 citations · Full text

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