Hereditary leiomyomatosis and renal cell cancer: an unusual and aggressive form of hereditary renal carcinoma

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

S. E. Olpin · Nature Genetics · 2002 · 1.6K citations

Urology, Uterine Fibroids, Somatic Variant +8

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

Jennifer S. Isaacs, Yun Jin Jung, David R. Mole et al. · Cancer Cell · 2005 · 935 citations · Full text

Urology, Renal Function, Fumarate Hydratase +6

Inherited susceptibility to uterine leiomyomas and renal cell cancer

Virpi Launonen, Outi Vierimaa, Maija Kiuru et al. · Proceedings of the National Academy of Sciences · 2001 · 670 citations · Full text

Mutations in the Fumarate Hydratase Gene Cause Hereditary Leiomyomatosis and Renal Cell Cancer in Families in North America

Jorge R. Toro, Michael L. Nickerson, Ming-Hui Wei et al. · The American Journal of Human Genetics · 2003 · 628 citations · Full text

Urology, North America, Medicine +6

Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency

Neyaz Alam · Human Molecular Genetics · 2003 · 315 citations

Cancer Pathology, Mcul Phenotype, Genetics +16