Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase

Improved protein–ligand docking using GOLD

Marcel L. Verdonk, Jason C. Cole, Michael J. Hartshorn et al. · Proteins Structure Function and Bioinformatics · 2003 · 3K citations · Full text

Novel Inhibitors of DNA Gyrase:  3D Structure Based Biased Needle Screening, Hit Validation by Biophysical Methods, and 3D Guided Optimization. A Promising Alternative to Random Screening

Hans-Joachim Boehm, Markus Boehringer, Daniel Bur et al. · Journal of Medicinal Chemistry · 2000 · 378 citations

Drug Target, Biochemistry, Hit Validation +15

Structural basis for altered activity of M‐ and H‐isozyme forms of human lactate dehydrogenase

Jon Read, V.J. Winter, C.M. Eszes et al. · Proteins Structure Function and Bioinformatics · 2001 · 331 citations

Aldehyde Dehydrogenase, Biochemistry, Human Lactate Dehydrogenase +14

Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity

Angus Cameron, Jon Read, R. Tranter et al. · Journal of Biological Chemistry · 2004 · 142 citations · Full text

Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum

Manuel S. Gomez, Robert C. Piper, Lucy A. Hunsaker et al. · Molecular and Biochemical Parasitology · 1997 · 134 citations

Selective Inhibition, Aldehyde Dehydrogenase, Biochemistry +6