PGE2 differentially regulates monocyte-derived dendritic cell cytokine responses depending on receptor usage (EP2/EP4)

IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells

Paweł Kaliński, Catharien M. U. Hilkens, A. J. Snijders et al. · The Journal of Immunology · 1997 · 602 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion

Chengcan Yao, Daiji Sakata, Yoshiyasu Esaki et al. · Nature Medicine · 2009 · 567 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs

Mark Abramovitz, Mohammed Adam, Yves Boie et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2000 · 557 citations · Full text

Life Sciences, Biochemistry, Pharmacology +10

Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells

Elke Scandella, Ying Men, Silke Gillessen et al. · Blood · 2002 · 498 citations · Full text

Life Sciences, Cell Biology, Immunology +11

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

Katia Boniface, Kristian Sass Bak‐Jensen, Ying Li et al. · The Journal of Experimental Medicine · 2009 · 475 citations · Full text

Life Sciences, Cell Biology, Immunology +13