Isoforms of c-KIT differ in activation of signalling pathways and transformation of NIH3T3 fibroblasts

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Richard S. Mann, Richard C. Mulligan, David Baltimore · Cell · 1983 · 1.8K citations

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Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

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Signal Transduction, Human Proto-oncogene C-kit, Cell Regulation +9

Direct Regulation of the <i>Akt</i> Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate

T. Franke, David R. Kaplan, Lewis C. Cantley et al. · Science · 1997 · 1.5K citations

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

Scott Kennedy, Andrew J. Wagner, Suzanne D. Conzen et al. · Genes & Development · 1997 · 1.1K citations · Full text

Growth Factor Receptors, Signal Transduction, Signaling Pathway +12

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

Asim Khwaja · The EMBO Journal · 1997 · 1K citations · Full text

Signal Transduction, Phosphoinositide 3-Oh Kinase, Signaling Pathway +15