Leonie K. Ashman

Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product.

T Furitsu, Tohru Tsujimura, T. Tono et al. · Journal of Clinical Investigation · 1993 · 818 citations · Full text

Immunology, Signaling Pathway, Cell Regulation +16

Regulation of Endothelial Cell Motility by Complexes of Tetraspan Molecules CD81/TAPA-1 and CD151/PETA-3 with α3β1 Integrin Localized at Endothelial Lateral Junctions

Marı́a Yáñez-Mó, Arántzazu Alfranca, Carlos Cabañas et al. · The Journal of Cell Biology · 1998 · 271 citations · Full text

Endothelial Cells, Cell Adhesion, Immunology +22

Juxtamembrane mutant V560GKit is more sensitive to Imatinib (STI571) compared with wild-type c-kit whereas the kinase domain mutant D816VKit is resistant.

Michelle J. Frost, Petranel T. Ferrão, Timothy P. Hughes et al. · PubMed · 2002 · 252 citations

Molecular Biology, Pathology, Cancer Biology +16

Localization of the Transmembrane 4 Superfamily (TM4SF) Member PETA-3 (CD151) in Normal Human Tissues: Comparison with CD9, CD63, and α5β1 Integrin

Paul M. Sincock, Graham Mayrhofer, Leonie K. Ashman · Journal of Histochemistry & Cytochemistry · 1997 · 191 citations

Integrin Beta1 Chain, Laboratory Immunology, Immunology +22

PETA-3/CD151, a member of the transmembrane 4 superfamily, is localised to the plasma membrane and endocytic system of endothelial cells, associates with multiple integrins and modulates cell function

Paul M. Sincock, Stephen Fitter, Robert G. Parton et al. · Journal of Cell Science · 1999 · 177 citations