Petranel T. Ferrão

Juxtamembrane mutant V560GKit is more sensitive to Imatinib (STI571) compared with wild-type c-kit whereas the kinase domain mutant D816VKit is resistant.

Michelle J. Frost, Petranel T. Ferrão, Timothy P. Hughes et al. · PubMed · 2002 · 252 citations

Medicine, Molecular Biology, Oncology +15

The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma

Rachel Ramsdale, Robert N. Jorissen, Frederic Z. Li et al. · Science Signaling · 2015 · 151 citations · Full text

Medicine, Cancer Biology, Oncology +17

Efficacy of CHK inhibitors as single agents in MYC-driven lymphoma cells

Petranel T. Ferrão, E P Bukczynska, Ricky W. Johnstone et al. · Oncogene · 2011 · 135 citations

Medicine, Cancer Biology, Oncology +16

Overexpression of P-glycoprotein in K562 cells does not confer resistance to the growth inhibitory effects of imatinib (STI571) in vitro

Petranel T. Ferrão, Michelle J. Frost, Shoo-Peng Siah et al. · Blood · 2003 · 85 citations

Life Sciences, Molecular Biology, Pharmacology +9

Constitutively active mutant D816VKit induces megakayocyte and mast cell differentiation of early haemopoietic cells from murine foetal liver

Petranel T. Ferrão, Thomas J. Gonda, Leonie K. Ashman · Leukemia Research · 2003 · 26 citations

Life Sciences, Cell Biology, Immunology +14