Concepedia

A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells

Yongzhong Liu, Pin Zhang, Jun Li, Ashok B. Kulkarni, Sylvain Perruche, Wanjun Chen

Nature Immunology · 2008 · 532 citations · 39 references

DOI

Concepts

References

39

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Jason D. Fontenot, Marc A. Gavin, Alexander Y. Rudensky · Nature Immunology · 2003 · 7.7K citations

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature · 2006 · 6.9K citations

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Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor <i>Foxp3 </i>

WanJun Chen, Wenwen Jin, Neil J. Hardegen et al. · The Journal of Experimental Medicine · 2003 · 4.6K citations · Full text

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Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

Marcia M. Shull, Ilona Ormsby, Ann B. Kier et al. · Nature · 1992 · 3K citations · Full text

, , +14

An essential role for Scurfin in CD4+CD25+ T regulatory cells

Roli Khattri, Tom Cox, Sue-Ann Yasayko et al. · Nature Immunology · 2003 · 2.8K citations

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