Incorporation of a phosphonic acid isostere of aspartic acid into peptides using Fmoc-solid phase synthesis

Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides

E. T. Kaiser, Robert L. Colescott, C.D. Bossinger et al. · Analytical Biochemistry · 1970 · 3.5K citations

Natural Sciences, Biochemistry, Protein Biochemistry +10

Specification of Molecular Chirality

R. S. Cahn, Christopher Kelk Ingold, V. Prelog · Angewandte Chemie International Edition in English · 1966 · 1.8K citations

Natural Sciences, Chemistry, Molecular Physics +8

Conversion of serine to stereochemically pure .beta.-substituted .alpha.-amino acids via .beta.-lactones

Lee D. Arnold, Thomas H. Kalantar, John C. Vederas · Journal of the American Chemical Society · 1985 · 180 citations

Natural Sciences, Biochemistry, Chemistry +11

Asymmetric Synthesis of (1-Aminoalkyl)phosphonic Acids via Asymmetric Aldol Reaction of (Isocyanomethyl)phosphonates Catalyzed by a Chiral Ferrocenylphosphine-Gold(I) Complex

Masaya Sawamura, Yoshihiko Ito, Tamio Hayashi · Tetrahedron Letters · 1989 · 119 citations

Natural Sciences, Chemistry, Catalysis +12

Farnesyl Diphosphate-Based Inhibitors of Ras Farnesyl Protein Transferase

Dinesh V. Patel, Robert J. Schmidt, Scott A. Biller et al. · Journal of Medicinal Chemistry · 1995 · 70 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6