Concepedia

Butyrate mediates Caco-2 cell apoptosis via up-regulation of pro-apoptotic BAK and inducing caspase-3 mediated cleavage of poly-(ADP-ribose) polymerase (PARP)

Frank M. Ruemmele, Serge Dionne, Ijaz A. Qureshi, D.S.R. Sarma, Emile Levy, Ernest G. Seidman

Cell Death and Differentiation · 1999 · 110 citations · 13 references

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki Miyashita, John C. Reed · Cell · 1995 · 4.1K citations · Full text

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Dual Signaling of the Fas Receptor: Initiation of Both Apoptotic and Necrotic Cell Death Pathways

Dominique Vercammen, Greet Brouckaert, Geertrui Denecker et al. · The Journal of Experimental Medicine · 1998 · 551 citations · Full text

Suppression of histone deacetylation in vivo and in vitro by sodium butyrate.

L.C. Boffa, G. Vidali, Robert S. Mann et al. · Journal of Biological Chemistry · 1978 · 480 citations · Full text

Effect of bcl-2 on Fas antigen-mediated cell death.

Norio Itoh, Yoshihide Tsujimoto, Shigekazu Nagata · The Journal of Immunology · 1993 · 434 citations · Full text

Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway.

Vanina A. Medina, B Edmonds, Graeme P. Young et al. · PubMed · 1997 · 379 citations

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