L.C. Boffa

Suppression of histone deacetylation in vivo and in vitro by sodium butyrate.

L.C. Boffa, G. Vidali, Robert S. Mann et al. · Journal of Biological Chemistry · 1978 · 480 citations · Full text

Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences.

G. Vidali, L.C. Boffa, E. Morton Bradbury et al. · Proceedings of the National Academy of Sciences · 1978 · 460 citations · Full text

Histone Modifications, Epigenetic Change, Genetics +25

Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats.

L.C. Boffa, J. R. Lupton, M. Mariani et al. · PubMed · 1992 · 179 citations

Nutrition, Gastroenterology, Pathology +17

Manifold effects of sodium butyrate on nuclear function. Selective and reversible inhibition of phosphorylation of histones H1 and H2A and impaired methylation of lysine and arginine residues in nuclear protein fractions.

L.C. Boffa, Rosemarie Gruss, V. G. Allfrey · Journal of Biological Chemistry · 1981 · 179 citations · Full text

Characterization of the non-histone nuclear proteins associated with rapidly labeled heterogeneous nuclear RNA.

Jonathan Karn, G. Vidali, L.C. Boffa et al. · Journal of Biological Chemistry · 1977 · 177 citations · Full text

Nuclear Structure, Genetics, Molecular Biology +23