L.C. Boffa

Suppression of histone deacetylation in vivo and in vitro by sodium butyrate.

L.C. Boffa, G. Vidali, Robert S. Mann et al. · Journal of Biological Chemistry · 1978 · 481 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequences.

G. Vidali, L.C. Boffa, E. Morton Bradbury et al. · Proceedings of the National Academy of Sciences · 1978 · 466 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats.

L.C. Boffa, J. R. Lupton, M. Mariani et al. · PubMed · 1992 · 179 citations

Life Sciences, Nutrition, Nutritional Sciences +14

Manifold effects of sodium butyrate on nuclear function. Selective and reversible inhibition of phosphorylation of histones H1 and H2A and impaired methylation of lysine and arginine residues in nuclear protein fractions.

L.C. Boffa, Rosemarie Gruss, V. G. Allfrey · Journal of Biological Chemistry · 1981 · 179 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Characterization of the non-histone nuclear proteins associated with rapidly labeled heterogeneous nuclear RNA.

Jonathan Karn, G. Vidali, L.C. Boffa et al. · Journal of Biological Chemistry · 1977 · 176 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9