Synthesis and polymerization of O6-methylguanosine 5′-diphosphate

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

A. Loveless · Nature · 1969 · 947 citations

O–6 Alkylation, Biochemistry, Medicine +6

Methylation of deoxyribonucleic acid in cultured mammalian cells by <i>N</i>-methyl-<i>N</i>′-nitro-<i>N</i>-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

P.D. Lawley, Carolyn J. Thatcher · Biochemical Journal · 1970 · 495 citations · Full text

Cellular Thiol Concentrations, Epigenetic Change, Dna Methylation +24

Conversion of Mono- and Oligodeoxyribonucleotides to 5'-Triphosphates¹

Donald E. Hoard, Donald G. Ott · Journal of the American Chemical Society · 1965 · 431 citations

Molecular Sciences, Bioorganic Chemistry, Engineering +15

Alkylation by propylene oxide of deoxyribonucleic acid, adenine, guanosine and deoxyguanylic acid

P.D. Lawley, Michael Jarman · Biochemical Journal · 1972 · 88 citations · Full text

Dimethyl Sulphate, Bioorganic Chemistry, Nucleic Acid Chemistry +14

Reaction of alkylating mutagens and carcinogens with nucleic acids: N-3 of guanine as a site of alkylation by N-methyl-N-nitrosourea and dimethyl sulphate

P.D. Lawley, D.J. Orr, S. A. Shah · Chemico-Biological Interactions · 1972 · 62 citations

Nucleic Acid Chemistry, Biochemistry, Natural Sciences +6