D.J. Orr

Specific excision of methylation products from DNA of Escherichia coli treated with N-methyl-N′-nitro-N-nitrosoguanidine

P.D. Lawley, D.J. Orr · Chemico-Biological Interactions · 1970 · 173 citations

Dna Sequencing, Natural Sciences, Dna Methylation +13

Isolation and identification of products from alkylation of nucleic acids: ethyl- and isopropyl-purines

P.D. Lawley, D.J. Orr, Michael Jarman · Biochemical Journal · 1975 · 109 citations · Full text

Bioorganic Chemistry, Engineering, Molecular Biology +18

Reaction products from <i>N</i>-methyl-<i>N</i>-nitrosourea and deoxyribonucleic acid containing thymidine residues. Synthesis and identification of a new methylation product, <i>O</i>4-methyl-thymidine

P.D. Lawley, D.J. Orr, S. A. Shah et al. · Biochemical Journal · 1973 · 102 citations · Full text

Bioorganic Chemistry, Engineering, Dna Methylation +24

Reaction of alkylating mutagens and carcinogens with nucleic acids: N-3 of guanine as a site of alkylation by N-methyl-N-nitrosourea and dimethyl sulphate

P.D. Lawley, D.J. Orr, S. A. Shah · Chemico-Biological Interactions · 1972 · 62 citations

Nucleic Acid Chemistry, Biochemistry, Natural Sciences +6

Methylation of nucleic acids by 2,2-dichlorovinyl dimethyl phosphate (dichlorvos, DDVP)

P.D. Lawley, S. A. Shah, D.J. Orr · Chemico-Biological Interactions · 1974 · 45 citations

Nucleic Acid Chemistry, Natural Sciences, Epigenetic Change +10