Concepedia

Infusion of FK506, a specific inhibitor of calcineurin, induces potent tau hyperphosphorylation in mouse brain

Jing Luo, Jie Ma, Dayu Yu, Fan Bu, Wen Zhang, Ling-Hui Tu, Qun Wei

Brain Research Bulletin · 2008 · 26 citations · 19 references

DOI

Concepts

References

19

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Jun S. Liu, Jesse D. Farmer, Willam S. Lane et al. · Cell · 1991 · 4.1K citations

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Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

Neil A. Clipstone · Nature · 1992 · 1.6K citations

, , +12

Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

Fei Liu, Inge Grundke‐Iqbal, Khalid Iqbal et al. · European Journal of Neuroscience · 2005 · 750 citations

, , +13

Alzheimer's disease and related disorders

Electroencephalography and Clinical Neurophysiology · 1990 · 118 citations

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IMMUNOPHILINS MAY LIMIT CALCINEURIN INHIBITION BY CYCLOSPORINE AND TACROLIMUS AT HIGH DRUG CONCENTRATIONS1

Lina Kung, Philip F. Halloran · Transplantation · 2000 · 98 citations

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