Expression and purification of exendin-4, a GLP-1 receptor agonist, in Escherichia coli

GLUCAGON-LIKE PEPTIDE-1 7-36: A PHYSIOLOGICAL INCRETIN IN MAN

Bernhard Kreymann, Mohammad A. Ghatei, Gareth Williams et al. · The Lancet · 1987 · 1.9K citations

Molecular Physiology, Physiology, Glucagon-like Peptide-1 7-36 +5

Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans.

Anne Flint, Anne Raben, Arne Astrup et al. · Journal of Clinical Investigation · 1998 · 1.4K citations · Full text

Nutrition, Promotes Satiety, Caloric Restriction +24

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

Gang Xu, Doris A. Stoffers, Joel F. Habener et al. · Diabetes · 1999 · 1.2K citations

Glucose Tolerance, Cellular Physiology, Insulin Signaling +19

Antidiabetogenic Effect of Glucagon-like Peptide-1 (7–36)amide in Normal Subjects and Patients with Diabetes Mellitus

M. Gutniak, Cathrine Ørskov, Jens J. Holst et al. · New England Journal of Medicine · 1992 · 868 citations · Full text

Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans

Michael A. Nauck, Ulrich Niedereichholz, Rainer Ettler et al. · American Journal of Physiology-Endocrinology and Metabolism · 1997 · 812 citations