Characterization of liposomal systems containing doxorubicin entrapped in response to pH gradients

Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential

Michael J. Hope, Marcel B. Bally, G. A. Webb et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1985 · 2.1K citations

Life Sciences, Biochemistry, Biophysics +13

Vesicles of variable sizes produced by a rapid extrusion procedure

L.D. Mayer, Michael J. Hope, Pieter R. Cullis · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1986 · 1.7K citations

Engineering, Materials Engineering, Membrane Trafficking +8

Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles

L.D. Mayer, Michael J. Hope, Pieter R. Cullis et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1985 · 433 citations

Natural Sciences, Biochemistry, Biophysics +11

Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient

L.D. Mayer, Marcel B. Bally, P.R. Cullis · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1986 · 376 citations

Life Sciences, Biochemistry, Cell Biology +11

Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice.

Lawrence D. Mayer, Linda C.L. Tai, Dicken S. C. Ko et al. · PubMed · 1989 · 355 citations

Pharmacy, Biochemistry, Pharmacology +17