Concepedia

Heat shock protein 70 genotypes HSPA1B and HSPA1L influence cytokine concentrations and interfere with outcome after major injury*

Ove Schröder, Klaus‐Martin Schulte, P. A. W. Ostermann, H. D. Röher, Axel Ekkernkamp, R. A. Laun

Critical Care Medicine · 2003 · 89 citations · 25 references

DOI

Abstract

The data indicate that genetic variations of the heat shock proteins HSPA1B and HSPA1L may contribute to clinical outcome after severe injury.

References

25

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference

Critical Care Medicine · 1992 · 4.8K citations

, , +13

HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine

Alexzander Asea, Stine‐Kathrein Kraeft, Evelyn A. Kurt‐Jones et al. · Nature Medicine · 2000 · 1.6K citations

, , +12

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

Helen M. Beere, Beni B. Wolf, Kelvin Cain et al. · Nature Cell Biology · 2000 · 1.5K citations · Full text

, , +11

A Mechanism for the Specific Immunogenicity of Heat Shock Protein-Chaperoned Peptides

Ryuichiro Suto, Pramod K. Srivastava · Science · 1995 · 821 citations

The Abbreviated Injury Scale and Injury Severity Score

Ellen J. MacKenzie, Sam Shapiro, James N. Eastham · Medical Care · 1985 · 618 citations

, , +14