Pathogenic role of HIF-1α in prostate hyperplasia in the presence of chronic inflammation

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O ₂ -Regulated Prolyl Hydroxylation

Panu Jaakkola, David R. Mole, Ya‐Min Tian et al. · Science · 2001 · 5.5K citations

The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression

Amparo Cano, Mirna Pérez‐Moreno, Isabel Rodrigo et al. · Nature Cell Biology · 2000 · 3.6K citations

Transcriptional Regulation, Developmental Biology, Signaling Pathway +11

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

Andrew Epstein, Jonathan Gleadle, Luke A. McNeill et al. · Cell · 2001 · 3.3K citations · Full text

Redox Signaling, Molecular Physiology, Mammalian Homologs Define +11

The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells

Eduard Batlle, Elena Sancho, Clara Francı́ et al. · Nature Cell Biology · 2000 · 2.6K citations

E-cadherin Gene Expression, Developmental Biology, Signaling Pathway +9

A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF

Richard K. Bruick, Steven L. McKnight · Science · 2001 · 2.5K citations

Chemical Biology, Redox Biology, Oxidative Stress +16