Distribution of topoisomerase II cleavage sites in simian virus 40 DNA and the effects of drugs

Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II

K M Tewey, Thomas C. Rowe, Liu Yang et al. · Science · 1984 · 1.5K citations

Medicine, Molecular Biology, Pharmacology +17

Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin.

Y H Hsiang, M G Lihou, Leroy F. Liu · PubMed · 1989 · 1K citations

Life Sciences, Cell Biology, Molecular Biology +17

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

Peter N. Cockerill, William T. Garrard · Cell · 1986 · 901 citations

Life Sciences, Genetics, Molecular Genetics +10

DNA topoisomerase II is required at the time of mitosis in yeast

Christian Holm, Takashi Goto, Jingjing Wang et al. · Cell · 1985 · 762 citations

Life Sciences, Cell Biology, Molecular Biology +11

Topoisomerase II is a structural component of mitotic chromosome scaffolds.

William C. Earnshaw, Brian Halligan, Carol Cooke et al. · The Journal of Cell Biology · 1985 · 761 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13