Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

Fouad Shalaby, Janet Rossant, Terry P. Yamaguchi et al. · Nature · 1995 · 3.9K citations

Angiogenesis, Blood-island Formation, Immunology +7

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

Guo‐Hua Fong, Janet Rossant, Marina Gertsenstein et al. · Nature · 1995 · 2.6K citations

Endothelial Cell Pathobiology, Angiogenesis, Signal Transduction +10

Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

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Breast Oncology, Mammary Gland Development, Medicine +10

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

Vladimir Joukov, Katri Pajusola, Arja Kaipainen et al. · The EMBO Journal · 1996 · 1.7K citations · Full text

Angiogenesis, Receptor Tyrosine Kinase, Immunology +9

LYVE-1, a New Homologue of the CD44 Glycoprotein, Is a Lymph-specific Receptor for Hyaluronan

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