Concepedia

Publication | Open Access

Effects of the mTOR inhibitor Rapamycin on Monocyte-Secreted Chemokines

DOIFull Paper Access

64

Citations

28

References

2014

Year

Hugo You‐Hsien Lin, Kai‐Ting Chang, Chi‐Chih Hung, Chang‐Hung Kuo, Shang‐Jyh Hwang, Hung‐Chun Chen, Chih‐Hsing Hung, Sheng‐Fung Lin
BMC Immunology

Abstract

Sirolimus downregulates the expression of chemokines in monocytes, including MCP-1, RANTES, IL-8, MIP-1α, and MIP-1β, by inhibiting the NF-κB-p65 and MAPK-p38 signalling pathways.

References

YearCitations

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