Chemokine-mediated redirection of T cells constitutes a critical mechanism of glucocorticoid therapy in autoimmune CNS responses

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

Andrea Reboldi, Caroline Coisne, Dirk Baumjohann et al. · Nature Immunology · 2009 · 1.2K citations

Life Sciences, Immunology, Molecular Biology +16

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

Laura Codarri Deak, Gábor Gyülvészi, Vinko Toševski et al. · Nature Immunology · 2011 · 1.2K citations

Life Sciences, Immunology, Neuroscience +17

In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines

Franck J. Barrat, André Boonstra, David F. Richards et al. · The Journal of Experimental Medicine · 2002 · 1.2K citations · Full text

Life Sciences, Cell Biology, Immunology +17

DNA Binding of the Glucocorticoid Receptor Is Not Essential for Survival

Holger M. Reichardt, Klaus H. Kaestner, Jan Tuckermann et al. · Cell · 1998 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

Mohamed El Behi, Bogoljub Ćirić, Hong Dai et al. · Nature Immunology · 2011 · 1.1K citations

Life Sciences, Cell Biology, Immunology +16