T cells are crucial for the anti-metastatic effect of anti-epidermal growth factor receptor antibodies

Molecular identification of a danger signal that alerts the immune system to dying cells

Yan Shi, James Evans, Kenneth L. Rock · Nature · 2003 · 1.6K citations

Inflammation, Immune Evasion, Systems Biology +14

Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck.

S. Huang, Jonathan M. Bock, Paul M. Harari · PubMed · 1999 · 718 citations

Pathology, Cell Proliferation, Cancer Biology +20

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radiosensitivity.

James Carmichael, William DeGraff, Adi F. Gazdar et al. · PubMed · 1987 · 701 citations

Engineering, Radiation Exposure, Pathology +24

Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice.

Paul Perrotte, Takayuki Matsumoto, Keiji Inoue et al. · PubMed · 1999 · 601 citations

Tumor Biology, Angiogenesis, Nude Mice +15

Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms.

Christiane J. Bruns, Matthew T. Harbison, Darren W. Davis et al. · PubMed · 2000 · 422 citations

Pathology, Dermatology, Anti-egf-r Antibody C225 +18