Concepedia

Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation

Ignacio Varela, Juan Cadiñanos, Alberto M. Pendás, Ana Gutiérrez‐Fernández, Alicia R. Folgueras, Luis Sánchez‐Pulido, Zhongjun Zhou, Francisco Rodríguez, Colin L. Stewart, José A. Vega,

Nature · 2005 · 467 citations · 25 references

DOI

Concepts

References

25

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

, , +15

Surfing the p53 network

Bert Vogelstein, David P. Lane, Arnold J. Levine · Nature · 2000 · 6.6K citations

, , +6

Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

Maria Eriksson, W. Ted Brown, Leslie B. Gordon et al. · Nature · 2003 · 2.2K citations · Full text

, , +5

Tumor spectrum analysis in p53-mutant mice

Tyler Jacks, Lee Ann Remington, Bart O. Williams et al. · Current Biology · 1994 · 2.1K citations

, , +12

Extension of Murine Life Span by Overexpression of Catalase Targeted to Mitochondria

Samuel E. Schriner, Nancy J. Linford, George M. Martin et al. · Science · 2005 · 1.7K citations

, , +17