Elevated Matrix Metalloproteinases and Collagen Fragmentation in Photodamaged Human Skin: Impact of Altered Extracellular Matrix Microenvironment on Dermal Fibroblast Function

Pathophysiology of Premature Skin Aging Induced by Ultraviolet Light

Gary J. Fisher, Zengquan Wang, Subhash C. Datta et al. · New England Journal of Medicine · 1997 · 1.5K citations · Full text

Medicine, Biochemistry, Dermatology +17

Molecular basis of sun-induced premature skin ageing and retinoid antagonism

Gary J. Fisher, Subhash C. Datta, Harvinder Talwar et al. · Nature · 1996 · 1.4K citations · Full text

Medicine, Dermatology, Molecular Biology +14

Collagen Fragmentation Promotes Oxidative Stress and Elevates Matrix Metalloproteinase-1 in Fibroblasts in Aged Human Skin

Gary J. Fisher, Taihao Quan, Trupta Purohit et al. · American Journal Of Pathology · 2008 · 463 citations · Full text

Veterinary Medicine, Cell Biology, Dermatology +15

Inhibition of Type I Procollagen Synthesis by Damaged Collagen in Photoaged Skin and by Collagenase-Degraded Collagen in Vitro

James Varani, Dara Spearman, Patricia Perone et al. · American Journal Of Pathology · 2001 · 330 citations · Full text

Medicine, Biochemistry, Dermatology +14

Reduced Fibroblast Interaction with Intact Collagen as a Mechanism for Depressed Collagen Synthesis in Photodamaged Skin

James Varani, Lucia Schuger, Michael K. Dame et al. · Journal of Investigative Dermatology · 2004 · 189 citations · Full text

Medicine, Cell Biology, Dermatology +10