Pathophysiology of Premature Skin Aging Induced by Ultraviolet Light

Gary J. Fisher, ZengQuan Wang, Subhash C. Datta, +3

New England Journal of Medicine

Molecular basis of sun-induced premature skin ageing and retinoid antagonism

Gary J. Fisher, Subhash C. Datta, Harvinder Talwar, +4

Nature

OphthalmologyCutaneous BiologyPhotocarcinogenesisMolecular BasisDermatology +3

Vitamin A Antagonizes Decreased Cell Growth and Elevated Collagen-Degrading Matrix Metalloproteinases and Stimulates Collagen Accumulation in Naturally Aged Human Skin1

James Varani, Roscoe L. Warner, Mehrnaz Gharaee‐Kermani, +7

Journal of Investigative Dermatology

Vitamin A AntagonizesAgingLongevityCutaneous BiologyExtracellular Matrix +9

Inhibition of Type I Procollagen Synthesis by Damaged Collagen in Photoaged Skin and by Collagenase-Degraded Collagen in Vitro

James Varani, Dara Spearman, Patricia Perone, +7

American Journal Of Pathology

Tissue EngineeringFibrosisDamaged CollagenCutaneous BiologyCollagenase-degraded Collagen +8

Application of Retinol to Human Skin In Vivo Induces Epidermal Hyperplasia and Cellular Retinoid Binding Proteins Characteristic of Retinoic Acid but Without Measurable Retinoic Acid Levels or Irritation

Sewon Kang, Gary J. Fisher, Subhash C. Datta, +7

Journal of Investigative Dermatology

PhotocarcinogenesisRetinoic AcidSkin PharmacologyWound HealingHuman Skin +4

c-Jun–dependent inhibition of cutaneous procollagen transcription following ultraviolet irradiation is reversed by all-trans retinoic acid

Gary J. Fisher, Subhash C. Datta, ZengQuan Wang, +5

Journal of Clinical Investigation

Collagen BreakdownImmunologyCutaneous Procollagen TranscriptionC-jun–dependent InhibitionDermatology +17

Collagen Degradation in Aged/Photodamaged Skin In Vivo and After Exposure to Matrix Metalloproteinase-1 In Vitro

Suzanne Fligiel, James Varani, Subhash C. Datta, +3

Journal of Investigative Dermatology

Tissue EngineeringEngineeringAged/photodamaged SkinCutaneous BiologyMatrix Metalloproteinase-1 +10

Ultraviolet Irradiation Increases Matrix Metalloproteinase-8 Protein in Human Skin In Vivo

Gary J. Fisher, Hye-Jung Choi, Zsuzsanna Bata‐Csörgõ, +5

Journal of Investigative Dermatology

Cutaneous BiologyPhotocarcinogenesisWound HealingDermatologyMatrix Biology +6

Sepsis-induced morbidity in mice: Effects on body temperature, body weight, cage activity, social behavior and cytokines in brain

Jill Granger, Pietro‐Luca Ratti, Subhash C. Datta, +2

Psychoneuroendocrinology

InflammationPsychoneuroimmunologyStress HormoneMedicineCage Activity +11

Lipopolysaccharide-induced increases in cytokines in discrete mouse brain regions are detectable using Luminex xMAP® technology

Subhash C. Datta, Mark R. Opp

Journal of Neuroscience Methods

InflammationKnockout MouseMedicineImmunologyLuminex Xmap® Technology +7