The evaluation of some pharmaceutically acceptable excipients as permeation enhancers for amoxicillin

Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure–activity relationship (QSAR) with the Abraham descriptors

Yuan H. Zhao, Joelle Le, Michael H. Abraham et al. · Journal of Pharmaceutical Sciences · 2001 · 521 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers

Bhagwant Rege, Joseph P. Y. Kao, James E. Polli · European Journal of Pharmaceutical Sciences · 2002 · 503 citations

Engineering, Biochemistry, Biophysics +16

Interactions of the Human Multidrug Resistance Proteins MRP1 and MRP2 with Organic Anions

Éva Bakos, Raymond Evers, Emese Sinkó et al. · Molecular Pharmacology · 2000 · 317 citations

Medicine, Biochemistry, Pharmacology +17

The Use of Surfactants to Enhance the Permeability of Peptides Through Caco-2 Cells by Inhibition of an Apically Polarized Efflux System

Manoj M. Nerurkar, Philip S. Burton, Ronald T. Borchardt · Pharmaceutical Research · 1996 · 284 citations

Pharmacy, Biochemistry, Cell Biology +12

Relationships between the hydrophilic–lipophilic balance values of pharmaceutical excipients and their multidrug resistance modulating effect in Caco-2 cells and rat intestines

Yu‐Li Lo · Journal of Controlled Release · 2003 · 234 citations

Pharmacy, Pharmaceutics, Pharmacology +17