Interactions of the Human Multidrug Resistance Proteins MRP1 and MRP2 with Organic Anions

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

Susan P.C. Cole, Gabu Bhardwaj, James H. Gerlach et al. · Science · 1992 · 3.1K citations

Medicine, Molecular Biology, Oncology +16

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

Marcel Kool, Marcel de Haas, George L. Scheffer et al. · PubMed · 1997 · 898 citations

Medicine, Molecular Biology, Oncology +15

Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

Coen C. Paulusma, Piter J. Bosma, Guido J.R. Zaman et al. · Science · 1996 · 832 citations

Medicine, Genetics, Molecular Genetics +17

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.

Susan P.C. Cole, Kathryn E. Sparks, Karen Fraser et al. · PubMed · 1994 · 774 citations

Medicine, Oncology, Pharmacology +15

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

G J Zaman, M J Flens, Manuel R. van Leusden et al. · Proceedings of the National Academy of Sciences · 1994 · 692 citations · Full text

Medicine, Oncology, Pharmacology +17