Concepedia

Identification of Orai1 Channel Inhibitors by Using Minimal Functional Domains to Screen Small Molecule Microarrays

Amir Masoud Sadaghiani, Sang Min Lee, Justin I. Odegaard, Dennis B. Leveson-Gower, Olivia M. McPherson, Paul Novick, Mi Ri Kim, Angela N. Koehler, Robert S. Negrin, Ricardo E. Dolmetsch,

Chemistry & Biology · 2014 · 60 citations · 32 references

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References

32

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

Stefan Feske, Yousang Gwack, Murali Prakriya et al. · Nature · 2006 · 2.2K citations

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STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

Jen Liou, Man Lyang Kim, Won Do Heo et al. · Current Biology · 2005 · 2.1K citations · Full text

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STIM1, an essential and conserved component of store-operated Ca2 <b>+</b> channel function

Jack Roos, Paul J. DiGregorio, Andriy V. Yeromin et al. · The Journal of Cell Biology · 2005 · 1.8K citations · Full text

Depletion of intracellular calcium stores activates a calcium current in mast cells

Markus Hoth, Reinhold Penner · Nature · 1992 · 1.7K citations

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STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

Shenyuan L. Zhang, Ying Yu, Jack Roos et al. · Nature · 2005 · 1.4K citations · Full text

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