AMP-activated Protein Kinase Contributes to UV- and H2O2-induced Apoptosis in Human Skin Keratinocytes

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell · 2003 · 3.8K citations · Full text

Signal Transduction, Control Cell Growth, Cell Division +10

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3K citations

Signal Transduction, Signaling Pathway, Cell Regulation +5

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

Reuben J. Shaw, Monica Kosmatka, Nabeel Bardeesy et al. · Proceedings of the National Academy of Sciences · 2004 · 1.7K citations · Full text

AMP-Activated Protein Kinase Induces a p53-Dependent Metabolic Checkpoint

Russell G. Jones, David R. Plas, Sara Kubek et al. · Molecular Cell · 2005 · 1.6K citations · Full text

Cell Regulation, Amp-activated Protein Kinase, Protein Kinase +5

TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

Ken Inoki, Hongjiao Ouyang, Tianqing Zhu et al. · Cell · 2006 · 1.4K citations

Signal Transduction, Cell Regulation, Signaling Pathway +11