Tumor necrosis factor (TNF) stimulates plasminogen activator inhibitor (PAI) production by endothelial cells and decreases blood fibrinolytic activity in the rat

An endotoxin-induced serum factor that causes necrosis of tumors.

E A Carswell, Lloyd J. Old, Robert Kassel et al. · Proceedings of the National Academy of Sciences · 1975 · 4.5K citations · Full text

Inflammation, Residual Endotoxin, Tumor Necrosis Factor +15

Modulation of endothelial cell hemostatic properties by tumor necrosis factor.

Peter P. Nawroth, D Stern · The Journal of Experimental Medicine · 1986 · 1.3K citations · Full text

Endothelial Cells, Immunology, Pathology +20

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

Bruce Beutler, David A. Greenwald, J D Hulmes et al. · Nature · 1985 · 1.1K citations

Inflammation, Cytokine, Tumour Necrosis Factor +13

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.

M P Bevilacqua, J S Pober, Gerard R. Majeau et al. · Proceedings of the National Academy of Sciences · 1986 · 1.1K citations · Full text

Vascular Disease, Endothelial Cells, Immunology +19

Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.

Jennifer R. Gamble, John M. Harlan, S J Klebanoff et al. · Proceedings of the National Academy of Sciences · 1985 · 1K citations · Full text

Immunology, Immune Regulation, Pathology +21