Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins.

Michael P. Neeper, Ann Marie Schmidt, J Brett, +6

Journal of Biological Chemistry

GlycobiologyMolecular BiologyGlycoproteomicsProtein ExpressionCell Surface Receptor +16

Modulation of endothelial cell hemostatic properties by tumor necrosis factor.

Peter P. Nawroth, D Stern

The Journal of Experimental Medicine

Endothelial CellsImmunologyPathologyInflammationThrombosis +18

Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins

S D Yan, Ann Marie Schmidt, Geoffrey M. Anderson, +5

Journal of Biological Chemistry

AgingLipid PeroxidationGlycobiologyImmunologyCell Death +19

Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes.

A.M. Schmidt, Osamu Hori, J X Chen, +7

Journal of Clinical Investigation

Vascular DiseaseImmunologyAccelerated VasculopathyAdvanced GlycationEndothelial Cell Surface +17

Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration.

Matthias Clauss, Marlene L. Gerlach, Herwig Gerlach, +7

The Journal of Experimental Medicine

ImmunologyPathologyTumor-derived PolypeptideTumor BiologyInflammation +17

Advanced Maillard reaction end products are associated with Alzheimer disease pathology.

Mark A. Smith, Shinji Taneda, Peggy L. Richey, +6

Proceedings of the National Academy of Sciences

Molecular BiologyNeurochemical BiomarkersAlzheimer Disease PathologyAlzheimer's DiseaseProtein Folding +15

Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1.

Peter P. Nawroth, Ilan Bank, Dean A. Handley, +3

The Journal of Experimental Medicine

Endothelial Cell ReceptorsEndothelial CellsImmunologyImmune RegulationPathology +16

Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity.

Peter P. Nawroth, Dean A. Handley, Charles T. Esmon, +1

Proceedings of the National Academy of Sciences

Endothelial CellsCell-surface Anticoagulant ActivityImmunologyImmune RegulationImmune System +20

Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy. Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats.

Jean‐Luc Wautier, Clotilde Zoukourian, Olivier Chappey, +6

Journal of Clinical Investigation

AgingEarly Vascular HyperpermeabilityOxidative StressInflammationVascular Hyperpermeability +15

Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke.

E. Sander Connolly, Christopher J. Winfree, Timothy A. Springer, +7

Journal of Clinical Investigation

Pmns ContributeImmunologyCerebrovascular DiseaseCerebral Vascular RegulationNeuroinflammation +19