Cellular senescence induced by cathepsin X downregulation

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251K citations

Protein Assembly, Natural Sciences, Structural Proteins +8

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.3K citations · Full text

Replicative Senescence, Developmental Biology, Aging +14

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

David A. Alcorta, Yue Xiong, Dawn E. Phelps et al. · Proceedings of the National Academy of Sciences · 1996 · 966 citations · Full text

Normal Human Fibroblasts, Replicative Senescence, Senescent Hdfs +14

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

Véronique Nogueira, Youngkyu Park, Chia-Chen Chen et al. · Cancer Cell · 2008 · 764 citations · Full text

Reductive Stress, Sensitizes Cells, Longevity +10

Tumor Cell–Derived and Macrophage-Derived Cathepsin B Promotes Progression and Lung Metastasis of Mammary Cancer

Olga Vasiljeva, Anna Papazoglou, Achim Krüger et al. · Cancer Research · 2006 · 370 citations · Full text