Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli

Nature

Protein AssemblyNatural SciencesStructural ProteinsBacteriophageMolecular Biology +6

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile, +7

Proceedings of the National Academy of Sciences

Replicative SenescenceDevelopmental BiologyAgingCell DivisionLongevity +12

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

David A. Alcorta, Yue Xiong, Dawn E. Phelps, +3

Proceedings of the National Academy of Sciences

Normal Human FibroblastsReplicative SenescenceSenescent HdfsDevelopmental BiologyCell Regulation +12

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

Véronique Nogueira, Youngkyu Park, Chia-Chen Chen, +5

Cancer Cell

Reductive StressSensitizes CellsLongevityMedicineApoptosis +8

Tumor Cell–Derived and Macrophage-Derived Cathepsin B Promotes Progression and Lung Metastasis of Mammary Cancer

Olga Vasiljeva, Anna Papazoglou, Achim Krüger, +9

Cancer Research

Increased activity of p53 in senescing fibroblasts.

Peter Atadja, Hubert Wong, Igor Garkavtsev, +2

Proceedings of the National Academy of Sciences

FibrosisAgingTotal P53 MrnaP53 Tumor-suppressor ProteinCell Death +9

Caveolin-1 Expression Negatively Regulates Cell Cycle Progression by Inducing G₀/G₁Arrest via a p53/p21^WAF1/Cip1-dependent Mechanism

Ferruccio Galbiati, Daniela Volonté, Jun Liu, +5

Molecular Biology of the Cell

Up-regulation of Caveolin Attenuates Epidermal Growth Factor Signaling in Senescent Cells

Woong‐Yang Park, Jeong‐Soo Park, Kyung-A Cho, +4

Journal of Biological Chemistry

Expression of Caveolin-1 Induces Premature Cellular Senescence in Primary Cultures of Murine Fibroblasts

Daniela Volonté, Kun Zhang, Michael P. Lisanti, +1

Molecular Biology of the Cell

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice

Lisa Sevenich, Uta Schurigt, Kathrin Sachse, +9

Proceedings of the National Academy of Sciences