Shear stress attenuates apoptosis due to TNFα, oxidative stress, and serum depletion via death-associated protein kinase (DAPK) expression

Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress.

David N. Ku, Don P. Giddens, Christopher K. Zarins et al. · Arteriosclerosis An Official Journal of the American Heart Association Inc · 1985 · 2.7K citations · Full text

Vascular Disease, Engineering, Fluid Mechanics +19

The Dynamic Response of Vascular Endothelial Cells to Fluid Shear Stress

C. F. Dewey, S. R. Bussolari, Michael A. Gimbrone et al. · Journal of Biomechanical Engineering · 1981 · 1.1K citations

Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries.

Seymour Glagov, C K Zarins, D. P. Giddens et al. · PubMed · 1988 · 1K citations

Vascular Disease, Engineering, Biomedical Engineering +19

Suppression of Apoptosis by Nitric Oxide via Inhibition of Interleukin-1β–converting Enzyme (ICE)-like and Cysteine Protease Protein (CPP)-32–like Proteases

Stefanie Dimmeler, Judith Haendeler, Michael Nehls et al. · The Journal of Experimental Medicine · 1997 · 805 citations · Full text

Nitric Oxide, Lipid Peroxidation, Apoptosis +22

Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells

Matthew J. Kuchan, John A. Frangos · American Journal of Physiology-Cell Physiology · 1994 · 520 citations

Endothelial Cells, Cytoskeleton, Cardiovascular Function +20