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Artificial Evolution of an Enzyme Active Site: Structural Studies of Three Highly Active Mutants of Escherichia coli Alkaline Phosphatase

Enzyme Active SiteArtificial EvolutionBiochemistryProtein FoldingNatural SciencesEnzyme CatalysisDirected EvolutionMolecular BiologySynthetic BiologyEnzyme SpecificityStructure-function Enzyme KineticsStructural StudiesMedicineStructural Biology