Interleukin-1β–Induced Mucin Production in Human Airway Epithelium Is Mediated by Cyclooxygenase-2, Prostaglandin E2 Receptors, and Cyclic AMP-Protein Kinase A Signaling

Human cyclooxygenase-2 cDNA.

Timothy Hla, Karen M. Neilson · Proceedings of the National Academy of Sciences · 1992 · 1.5K citations

Life Sciences, Cell Biology, Molecular Biology +12

Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse

Scott G. Morham, Robert Langenbach, Charles D. Loftin et al. · Cell · 1995 · 1.1K citations · Full text

Medicine, Molecular Biology, Molecular Genetics +13

IL‐1β mediated up‐regulation of HIF‐lα via an NFkB/COX‐2 pathway identifies HIF‐1 as a critical link between inflammation and oncogenesis

Yunjin Jung, Jennifer S. Isaacs, Sunmin Lee et al. · The FASEB Journal · 2003 · 675 citations

Medicine, Cancer Biology, Oncology +17

Epidermal growth factor system regulates mucin production in airways

Kiyoshi Takeyama, Karim Dabbagh, Heung‐Man Lee et al. · Proceedings of the National Academy of Sciences · 1999 · 580 citations

Life Sciences, Cell Biology, Pharmacology +14

Mild and Moderate Asthma Is Associated with Airway Goblet Cell Hyperplasia and Abnormalities in Mucin Gene Expression

Claudia L. Ordoñez, Ramin Khashayar, Hofer Wong et al. · American Journal of Respiratory and Critical Care Medicine · 2001 · 580 citations

Medicine, Molecular Biology, Pathology +13