Concepedia

Effects of small interfering RNA targeting sphingosine kinase-1 gene on the animal model of Alzheimer’s disease

Yuan Zhang, Qian Yu, Tianbao Lai, Yang Yang, Gang Li, Shenggang Sun

Journal of Huazhong University of Science and Technology [Medical Sciences] · 2013 · 18 citations · 15 references

DOI

Concepts

References

15

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Ganesh M. Shankar, Shaomin Li, Tapan Mehta et al. · Nature Medicine · 2008 · 3.7K citations · Full text

, , +14

Correlation Between Elevated Levels of Amyloid β-Peptide in the Brain and Cognitive Decline

Jan Näslund · JAMA · 2000 · 1.3K citations

, , +12

Molecular Cloning and Functional Characterization of a Novel Mammalian Sphingosine Kinase Type 2 Isoform

Hong Liu, Masako Sugiura, Victor E. Nava et al. · Journal of Biological Chemistry · 2000 · 665 citations · Full text

, , +14

Deregulation of sphingolipid metabolism in Alzheimer's disease

Xingxuan He, Yu Huang, Bin Li et al. · Neurobiology of Aging · 2008 · 530 citations

, , +12

Regulation of cholesterol and sphingomyelin metabolism by amyloid-β and presenilin

Marcus O.W. Grimm, Heike S. Grimm, Andreas Jochem Pätzold et al. · Nature Cell Biology · 2005 · 447 citations

, , +12